銆€銆€2005骞滁/span> 鏄屽钩鍩哄湴閫氳繃GMP璁よ瘉;鍏徃瀹屾垚鑲℃潈鍒嗙疆鏀归潻锛屾敞鍐岃祫閲戝彉鏇翠负8280涓囧厓锛涘叕鍙歌懀浜嬮暱寰愭槑娉㈠厛鐢熻幏鍖椾含甯傜涓夊眾浼樼闈掑勾浼佷笟瀹?閲戝)绉板彿锛涚洂閰告墭鐑峰徃鐞兼敞灏勬恫銆佺幆瀛㈢礌杞兌鍥娿€佹敞灏勭敤鑳歌吅浜旇偨鍜岃兏鑵轰簲鑲芥敞灏勬恫銆佹敞灏勭敤鐢熼暱鎶戠礌鍜岀敓闀挎姂绱犳敞灏勬恫銆佹敞灏勭敤鏋滅硸浜岀７閰搁挔銆佸凹楹﹁鏋楃瓑鑾锋壒涓婂競锛涘叕鍙稿噣鍒╂鼎3382涓囧厓锛汓/p>

銆€銆€2006骞滁/span> 鍦ㄦ勃娣变袱甯傞瀹跺叕甯冨苟鎴愬姛瀹炴柦鑲＄エ鏈熸潈婵€鍔辫鍒掞紱娉ㄥ皠鐢ㄩ棬鍐叞鑳洪叾銆佺传鏉夐唶娉ㄥ皠娑层€侀厭鐭抽吀闀挎槬鐟炴花娉ㄥ皠娑层€佺洂閰镐紣鏄旀礇闊︾墖銆侀樋濂囬湁绱犺兌鍥婄瓑17涓搧绉嶈幏涓婂競锛涘叕鍙稿噣鍒╂鼎4785涓囧厓;

銆€銆€2007骞滁/span> 鍏ラ€夊寳浜競涓叧鏉戠鎶€鍥尯鐧惧鍒涙柊鍨嬭瘯鐐逛紒涓欫鑽ｈ幏鍖椾含甯傜撼绋庨噸鐐逛紒涓氾紱鎺ц偂瀛愬叕鍙稿弻楣珛鐢熻幏銆婅嵂鍝丟MP璇佷功銆婝鍏徃鍑€鍒╂鼎棣栨绐佺牬1浜垮厓锛岃揪1.35浜垮厓;

銆€銆€2008骞滁/span> 寰愭槑娉㈣懀浜嬮暱鑽ｈ幏棣栭兘“鍔冲姩濂栫珷”锛涘叕鍙稿噣鍒╂鼎棣栨绐佺牬2浜垮厓;寰愭槑娉㈣懀浜嬮暱鍏ラ€?ldquo;鏂颁笘绾櫨鍗冧竾浜烘墠宸ョ▼”鍥藉绾т汉閫夛紱闃垮痉绂忛煢閰兌鍥娿€佸埄濉炵７閰搁挔銆佹皑閰氭洸椹銆佸悧鏇块害鑰冮厷閰€佹敞灏勭敤涓夋哀鍖栦簩鐮风瓑鏂拌嵂鑾锋壒涓婂競;鍏徃鍑€鍒╂鼎2.18浜垮厓锛汓/p>

銆€銆€2009骞滁/span> 鍏徃鍙婂緪鏄庢尝鎬荤粡鐞嗗弻鍙岃崳鑾?ldquo;涓叧鏉戠鎶€鍥尯20鍛ㄥ勾绐佸嚭璐＄尞濂?rdquo;锛涘叕鍙稿叆閫夐鎵逛腑鍏虫潙鍥藉鑷富鍒涙柊绀鸿寖鍖哄垱鏂板瀷璇曠偣浼佷笟锛涜崳鑾烽娓?quot;閲戠传鑽嗗"鏈€浣充腑灏忓瀷涓婂競浼佷笟锛涙潖鐏垫淮涓搞€佺幆瀛㈢礌杞兌鍥婄瓑鑾锋壒涓婂競锛涘嚭璧?020涓囧厓鎶曡祫杈藉畞杩堣开鐢熺墿绉戞妧鑲′唤鏈夐檺鍏徃(48.57%)锛涘叕鍙稿噣鍒╂鼎2.63浜垮厓锛汓/p>

銆€銆€2010骞滁/span> 鍏ラ€夊寳浜敓鐗╁尰鑽骇涓氳法瓒婂彂灞曞伐绋?G20 宸ョ▼)锛涜璁ゅ畾涓哄浗瀹剁伀鐐鍒掗噸鐐归珮鏂版妧鏈紒涓氾紱鍏ラ€変腑鍥芥渶鍏风珵浜夊姏鍖昏嵂涓婂競浼佷笟绗簲鍚嶏紱闃垮痉绂忛煢閰墖鑾锋柊鑽瘉涔﹀拰鐢熶骇鎵逛欢锛岄唻閰稿ゥ鏇茶偨绛夎幏鎵逛笂甯傦紱鍑鸿祫1000涓囧厓鎶曡祫闀块鑽笟鑲′唤鏈夐檺鍏徃(6.57%);鍑鸿祫1000涓囧厓鎶曡祫鍗椾含鍗℃枃杩鏈夐檺鍏徃(40%)鎶曟潈锛涘叕鍙稿噣鍒╂鼎2.73浜垮厓锛汓/p>

銆€銆€2011骞滁/span> 鎶€鏈腑蹇冭璁ゅ畾涓哄浗瀹剁骇浼佷笟鎶€鏈腑蹇冿紱鍑鸿祫300涓囩編鍏冭绔嬬編(鐗规媺鍗?瀛愬叕鍙 (DIAPIN THERAPEUTICS,LLC )寮€灞曞垱鏂板瀷绯栧翱鐥呰嵂鐗╃爺绌讹紱鍏徃鍑€鍒╂鼎绐佺牬5浜垮厓锛涘叆閫変腑鍥芥渶鍏风珵浜夊姏鍖昏嵂涓婂競浼佷笟绗洓鍚嶏紱鑽ｈ幏棣欐腐"閲戠传鑽嗗"鏈€浣充腑灏忓瀷涓婂競浼佷笟锛涙浛鑾攽鑳鸿幏鎵逛笂甯傦紱鍏徃鍑€鍒╂鼎5.23浜垮厓锛汓/p>

銆€銆€2012骞滁/span> 鏄屽钩鍩哄湴鐢熶骇杞﹂棿閫氳繃鏂扮増GMP璁よ瘉锛涙垚鍔熸寫鎴樺浗澶栦笓鍒╃爺鍙戝搧绉嶆潵閭ｅ害鑳恒€佽揪娌欐浛灏艰幏寰椾复搴婅瘯楠屾壒鏂囷紱鍏徃閿€鍞敹鍏ョ獊鐮?0浜垮厓锛涘嚭璧?000涓囧厓鎶曡祫鍖椾含钂欏崥娑︾敓鐗╃鎶€鏈夐檺鍏徃(34%)锛涘嚭璧?200涓囧厓璁剧珛鏂颁埂鍙岄弓鐢熺墿鎶€鏈湁闄愬叕鍙?70%)锛汓span style="font-size: 12pt;">鍏徃鍑€鍒╂鼎4.81浜垮厓锛汓/span>

銆€銆€2013骞滁/span> 寰愭槑娉㈣懀浜嬮暱鍏ラ€夌鎶€鍖椾含鐧惧悕棰嗗啗浜烘墠(鐢熺墿鍖昏嵂)锛涙柊涔″師鏂欒嵂鍩哄湴銆佸姞鎷垮ぇ鎺ц偂瀛愬叕鍙窹nuVax SL鑾峰緱鐢熶骇璁稿彲璇侊紱鏄屽钩鍩哄湴寮曡繘鐨勬剰澶у埄渚濈帥鍏ㄨ嚜鍔ㄧ亴瑁呭強鍐诲共鐢熶骇绾垮畬鎴愬畨瑁呰皟璇曟嫙璁よ瘉鎶曚骇锛涘嚭璧?000涓囧厓鎶曡祫鍖椾含宕囧痉寮樹俊鍒涗笟鎶曡祫涓績(11.41%)锛涘叕鍙稿噣鍒╂鼎5.77浜垮厓锛汓/p>

銆€銆€2014骞滁/span> 寰愭槑娉㈣懀浜嬮暱鍏ラ€夋帹鍔ㄥ寳浜垱閫犵殑绉戞妧浜虹墿锛涘叕鍙歌璇勪负鍖椾含甯傞鎵?ldquo;G20”浼樼浼佷笟骞跺叆閫?ldquo;G20”浜屾湡宸ョ▼锛涘叕鍙歌璁ゅ畾涓哄浗瀹舵妧鏈垱鏂扮ず鑼冧紒涓氾紱寰愭槑娉㈣懀浜嬮暱绛夊洓浜哄叆閫夋捣娣€鍖?ldquo;娴疯嫳浜烘墠”璁″垝锛涢噸缁勪汉纰辨€ф垚绾ょ淮缁嗚優鐢熼暱鍥犲瓙鍑濊兌澶栫敤鍑濊兌鍓傝幏鎵逛笂甯傦紝鑱氫箼浜岄唶閲嶇粍浜虹矑缁嗚優闆嗚惤鍒烘縺鍥犲瓙娉ㄥ皠娑?琛ュ厖)鑾峰緱涓村簥鎵逛欢锛屾潵閭ｅ害鑳鸿兌鍥娿€佷笝閰稿€嶆隘绫虫澗姘旈浘鍓傜瓑5涓搧绉嶇敵鎶ョ敓浜с€傚叕鍙稿噣鍒╂鼎6.95浜垮厓锛汓/p>

銆€銆€2015骞滁/span> 涓叧鏉戞牳蹇冨尯鐢熺墿宸ョ▼鍜屾柊鍖昏嵂浜т笟鑱旂洘鎴愮珛锛屽弻楣嵂涓氬綋閫夌悊浜嬮暱鍗曚綅锛涜璁ゅ畾涓哄寳浜競楂樻柊鎶€鏈垚鏋滆浆鍖栫ず鑼冧紒涓氾紱鍥藉浜岀被鏂版壎娴庡鍑濊兌姝ｅ紡涓婂競锛涘叕鍙歌崳鑾?014骞村害(绗?7灞?涓浗涓婂競鍏徃閲戠墰濂?鍩轰笟闀块潚銆佹渶楂樻晥鐜囥€佹渶浣充紒涓氶琚栥€佹渶浣宠懀绉?锛涜崳鑾稶nilab璇勯€夌殑2014骞村害鍏ㄧ悆浼樼渚涘簲鍟嗗锛涘緪鏄庢尝钁ｄ簨闀垮叆閫?014骞村寳浜?ldquo;楂樺垱璁″垝--绉戞妧鍒涙柊鍙婄鎶€鍒涗笟棰嗗啗浜烘墠”锛涘嚭璧?21.89涓囩編鍏冩姇璧勭編鍥紻IAPIN THERAPEUTICS, LLC.(30%)锛涘嚭璧?800涓囧厓鎶曡祫涓婃捣淇″繝鍖昏嵂绉戞妧鏈夐檺鍏徃(30%)锛涘嚭璧?000涓囧厓鎶曡祫澶╂触鏃朵唬鎬¤绉戞妧鑲′唤鏈夐檺鍏徃(20%)锛涘叕鍙稿噣鍒╂鼎5.75浜垮厓锛汓/p>

銆€銆€2016骞滁/span> 寰愭槑娉㈣懀浜嬮暱褰撻€夊寳浜競绉戝崗鍓富甯紱鍑鸿祫1000涓囧厓鎶曡祫鍖椾含搴锋槑鐧惧ゥ鏂拌嵂鐮斿彂鏈夐檺鍏徃(8.70%)锛涘嚭璧?750涓囧厓鎶曡祫鍖椾含宕囧痉鑻辩洓鍒涗笟鎶曡祫鏈夐檺鍏徃(37.95%)锛涗緷璇鸿倽绱犻挔鍘熸枡鍙婃敞灏勬恫銆佸瑗夸粬璧涙敞灏勬恫鑾锋壒涓婂競锛岀憺鎴堥潪灏笺€佹硦椹害鑳恒€佸瘜椹吀鏇胯绂忛煢閰€佸崱鏍煎垪鍑€銆佽揪鏍煎垪鍑€绛夊搧绉嶈幏寰椾复搴婃壒鏂囥€傚叕鍙稿噣鍒╂鼎4.52浜垮厓;

銆€銆€2017骞滁/span> 鎸戞垬鍥介檯涓撳埄浜у搧“鏉ラ偅搴﹁兒”涓婂競锛涘瑗夸粬璧涙敞灏勬恫鑾锋壒涓婂競锛涙浛璇虹闊﹂叝鍘熸枡鑽幏寰楁敞鍐屾壒浠讹紱鍒╀紣娌欑彮鐗囥€佸煿闂ㄥ啲閰舵敞灏勬恫鑾峰緱涓村簥鎵逛欢锛涙柊涔″師鏂欒嵂鍩哄湴鏈?涓搧绉嶈幏寰楃敓浜ф壒浠跺苟閫氳繃GMP璁よ瘉鍜屾寮忔姇浜э紱鍑鸿祫500涓囧厓鎶曡祫閲嶅簡娴﹁缁寸敓鐗╃鎶€鏈夐檺鍏徃(10%)锛屽嚭璧?200涓囧厓鎶曡祫鍖椾含鍘熷垱瀹㈣偂鏉冩姇璧勫熀閲戠鐞嗕腑蹇?17.14%)锛涘叕鍙稿噣鍒╂鼎5.34浜垮厓;

銆€銆€2018骞滁/span> 涓惧姙鏉ラ偅搴﹁兒涓婂競鎺ㄤ粙浼氾紱鍙岄弓鑽笟鑽ｈ幏“鍖椾含绾㈠績鐩搁€氬叕鐩婂熀閲戜細”棰佸彂鐨?017骞?ldquo;骞村害鍏泭鎻村姪鐖卞績浼佷笟”銆?ldquo;骞村害鍏泭浼欎即”涓ら」鑽ｈ獕锛涘彂璧疯绔?ldquo;鍖椾含绔嬬敓鎱堝杽鍩洪噾浼?rdquo;锛涙寫鎴樺師鐮斾笓鍒╂姉鑲跨槫鑽ぇ鍝佺鏉ラ偅搴﹁兒鐨勭爺绌躲€佹敞灏勭敤閲嶇粍鍑濊鍥犲瓙VII(杞熀鍥犲厰)涓村簥鍓嶇爺绌躲€侀暱鏁堥噸缁勪汉淇冪孩缁嗚優鐢熸垚绱犵殑涓村簥鍓嶇爺绌跺悓鏃堕€氳繃鍥藉绉戞妧閲嶅ぇ涓撻」璇勫锛涘瑗夸粬璧涙敞灏勬恫鑾锋壒涓婂競鍏ㄤ汉鎶桟TLA-4 鍗曞厠闅嗘姉浣撴敞灏勬恫(浼婂尮鍗曟姉)“鑽墿涓村簥璇曢獙鎵逛欢”锛涢暱鏁堥噸缁勪汉淇冨嵉娉℃縺绱?rhFSH-CTP)娉ㄥ皠娑?ldquo;鑽墿涓村簥璇曢獙鎵逛欢”锛涘嚭璧?1,900涓囧厓鍙備笌璁剧珛鍩洪噾鍢夊叴棰愬拰鑲℃潈鎶曡祫鍩洪噾鍚堜紮浼佷笟(35.23%)锛屽叕鍙稿噣鍒╂鼎5.71浜垮厓锛汓/p>

銆€銆€2019骞滁/span> 澶у叴鍩哄湴鑾峰緱鐢熶骇璁稿彲璇侊紱闈炲竷鍙镐粬鑾风編鍥紽DA鏆傛椂鎵瑰噯;濂ョ鍞戣幏鎵逛笂甯傦紱闂ㄥ啲鑳板矝绱犲強绯诲垪鍒跺墏銆佸嵉娉℃縺绱犺幏鎵逛复搴婏紱瀵岄┈閰告浛璇虹闊︿簩鍚″憢閰墖銆侀樋寰风闊﹂叝鐗?鑳跺泭銆佷緷璇鸿倽绱犻挔娉ㄥ皠娑层€佸埄浼愭矙鐝墖銆佹浛鑾攽鑳鸿兌鍥娿€佹潵閭ｅ害鑳鸿兌鍥娿€佸ゥ纭濆攽娉ㄥ皠娑插畬鎴愪竴鑷存€ц瘎浠峰苟鐢虫姤銆侟/p>